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Grief is the anguish experienced after significant loss, usually the death of a beloved person.
Grief often includes physiological distress, separation anxiety, confusion, yearning, obsessive dwelling on the past, and apprehension about the future. Intense grief can become life-threatening through disruption of the immune system, self-neglect, and suicidal thoughts.
Grief may also take the form of regret for something lost, remorse for something done, or sorrow for a mishap to oneself.
Adapted from the APA Dictionary of Psychology